2014•Reproductive Biology and EndocrinologyOpen access

Recombinant luteinizing hormone supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection with gonadotropin releasing hormone antagonist protocol: a systematic review and meta-analysis

Yujing Xiong, Zhiqin Bu, Wei Dai, Meixiang Zhang, Xiao Bao, Yingpu Sun

Abstract

The objective of this meta-analysis is to assess the impact of LH supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with gonadotropin releasing hormone (GnRH) antagonist protocol. No significant difference in outcomes between LH supplementation and r-FSH alone in women undergoing IVF/ICSI with GnRH antagonist protocol is currently present, and further studies are necessary for more solid conclusions on pregnancy likelihood to be drawn.

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Available abstract

Key concepts: Intracytoplasmic sperm injection, In vitro fertilisation, Luteinizing hormone, Gonadotropin-releasing hormone antagonist, Hormone antagonist, Andrology, Gonadotropin, Gonadotropin-releasing hormone