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2004•Anales De La Asociacion Quimica ArgentinaRequires access

O-SULFATION OF 4-O-SUBSTITUTED DERIVATIVES OF D-GLUCURONIC ACID

Natalia Salmaso, Mariano J. L. Castro, José Kovensky, Alicia Fernández Cirelli

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Abstract

The sulfation of heparan sulfate, 2-sulfation of D-glucuronic acid, is regioselective as has been reported. 4-O-substituted D-glucuronic acid derivatives were synthetized in this work to study the sulfation of monosacharide models. No selectivity between hydroxyls 2- and 3- was obtained.

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What this paper is about

The sulfation of heparan sulfate, 2-sulfation of D-glucuronic acid, is regioselective as has been reported. 4-O-substituted D-glucuronic acid derivatives were synthetized in this work to study the sulfation of monosacharide models. No selectivity between hydroxyls 2- and 3- was obtained.

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Available abstract

The sulfation of heparan sulfate, 2-sulfation of D-glucuronic acid, is regioselective as has been reported. 4-O-substituted D-glucuronic acid derivatives were synthetized in this work to study the sulfation of monosacharide models. No selectivity between hydroxyls 2- and 3- was obtained.

Key concepts: Sulfation, Glucuronic acid, Chemistry, Regioselectivity, Selectivity, Sulfate, Glucuronates, Organic chemistry

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