2005•Journal of Clinical MicrobiologyOpen access

Diagnostic and Therapeutic Pitfalls Associated with Primaquine-Tolerant Plasmodium vivax

Jeanne M. Spudick, Lynne S. Garcia, David M. Graham, David A. Haake

Abstract

We describe a U.S. Army Ranger returning from duty in Afghanistan and Iraq with life-threatening infection due to Plasmodium vivax. Morphological variants were observed in blood films prepared using samples collected by venipuncture. The patient's multiple relapses indicate infection with primaquine-tolerant P. vivax. Strategies for relapse prevention using primaquine are reviewed.

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Key concepts: Primaquine, Plasmodium vivax, Venipuncture, Malaria, Medicine, Vivax malaria, Virology, Immunology