Rare Case Reports of Non Syndromic Hypodontia - Genes at Work

Agenesis of one or more permanent teeth is a common developmental dental anomaly in human beings. In the literature, many terms are used to describe missing teeth like oligodontia, anodontia, aplasia of teeth, congenitally missing teeth, absence of teeth, agenesis of teeth and lack of teeth. The etiology of missing teeth may be environmental factors like infection, trauma, drugs, chemotherapy or radiotherapy or may be genetic. The most often missing permanent teeth, excluding third molars, are the second premolars and the lateral incisors. Here we report two cases of hypodontia of permanent teeth which are familial and without the presence of any syndrome. We have also reviewed literature of similar cases published till date.