2013Bangladesh Journal of Medical BiochemistryOpen access

Cystatin C -a Promising Marker of Glomerular Filtration Rate

Nowrase Jahan, Sohani Ferdousi

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Abstract

Glomerular filtration rate (GFR) is the best single measure of overall function of kidney. GFR is routinely assessed by measuring the concentration of endogenous serum markers such as blood urea nitrogen and serum creatinine (SCr). Although widely used these endogenous marker are not ideal and do not perform optimally in certain clinical settings. The purpose of this review is to critically review the potential utility of Cys C as a new promosing markers of GFR and to review whether Cys C had any advantage over routinely used endogenous marker in different population group. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13284 Bangladesh J Med Biochem 2013; 6(1): 26-30

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Glomerular filtration rate (GFR) is the best single measure of overall function of kidney. GFR is routinely assessed by measuring the concentration of endogenous serum markers such as blood urea nitrogen and serum creatinine (SCr). Although widely used these endogenous marker are not ideal and do not perform optimally in certain clinical settings. The purpose of this review is to critically review the potential utility of Cys C as a new promosing markers of GFR and to review whether Cys C had any advantage over routinely used endogenous marker in different population group. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13284 Bangladesh J Med Biochem 2013; 6(1): 26-30

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Available abstract

Glomerular filtration rate (GFR) is the best single measure of overall function of kidney. GFR is routinely assessed by measuring the concentration of endogenous serum markers such as blood urea nitrogen and serum creatinine (SCr). Although widely used these endogenous marker are not ideal and do not perform optimally in certain clinical settings. The purpose of this review is to critically review the potential utility of Cys C as a new promosing markers of GFR and to review whether Cys C had any advantage over routinely used endogenous marker in different population group. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13284 Bangladesh J Med Biochem 2013; 6(1): 26-30

Key concepts: Renal function, Cystatin C, Creatinine, Endogeny, Blood urea nitrogen, Medicine, Internal medicine, Population

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