1970•Journal of Dhaka Medical CollegeOpen access

Study of Sensitivity Pattern of Metronidazole on Axenic Culture of Entamoeba Histolytica In Vitro

SK Sarker, Dinesh Mondal, M. Zia Siddique

Abstract

Objective: To evaluate the sensitivity pattern of metronidazole against Entamoeba histolytica. Design: It was an experimental study. Settings: The study was carried out in Parasitology Laboratory, ICDDR,B Dhaka from January 2007 to June 2007. Subjects: Entamoeba histolytica (Strain: MS 27 5030) Main outcome measure: Minimum inhibitory concentration (MIC). Results: In this study MIC of metronidazole was < 0.08 mg/ml. Conclusion: The result suggests that metronidazole is still the standard drug for treatment of amoebiasis Key words: Axenic culture; Entamoeba histolytica; Metronidazole. DOI: 10.3329/jdmc.v19i1.6256 J Dhaka Med Coll. 2010; 19(1) : 65-66.

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Key concepts: Entamoeba histolytica, Metronidazole, Axenic, Amoebiasis, Microbiology, Medicine, Entamoeba, Antibiotics