1985•Poultry ScienceOpen access

Cyproheptadine Stimulated Prolactin Release in the Young Turkey (Meleagris gallopavo)

S.C. Fehrer, J.L. Silsby, M. E. El Halawani

Abstract

Cyproheptadine (CHD) at doses of .1 to 10.0 mg/kg body weight produced a dose-related elevation in prolactin (PRL) and no change in luteinizing hormone (LH) levels. Cyproheptadine pretreatment failed to depress the quipazine (serotonin agonist)-induced PRL rise. Rather than inhibiting the serotonergic induction of PRL release in the young turkey, CHD exerted a stimulatory influence on PRL release through another mechanism.

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Key concepts: Cyproheptadine, Quipazine, Prolactin, Meleagris gallopavo, Endocrinology, Serotonergic, Internal medicine, Chemistry