2006•The Journal of Headache and PainOpen access

Spontaneous splenic infarction associated with sumatriptan use

Ankur Arora, Shalabh Arora

Abstract

Triptans are specific agonists of the serotonergic 5-HT(1B/1D) receptors that have increasingly been used in the treatment of migraine and cluster headaches. Though they are generally considered safe, there have been a few reports of myocardial infarction and stroke associated with triptan use. We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.

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Key concepts: Sumatriptan, Triptans, Medicine, Migraine, Cluster headache, Neurology, Stroke (engine), Headaches