1997•Chemical and Pharmaceutical BulletinOpen access
Alkaloidal Constituents of the Leaves of Stephania cepharantha Cultivated in Japan: Structure of Cephasugine, a New Morphinane Alkaloid.
Noriaki Kashiwaba, Shigeo Morooka, Minoru Ōno, Jun Toda, Hideki Suzuki, Takehiro Sano
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Abstract
From the leaves of Stephania cepharantha HAYATA (Menispermaceae) cultivated in Japan, a new morphinane alkaloid, cephasugine (1), was isolated together with 14 known alkaloids. The structure of 1 was elucidated as the N-methyl derivative of sinococuline (17) by comparison of spectroscopic data with those of cephakicine (16). This is the first report of the alkaloidal constituents of the leaves of S. cepharantha.
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