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2012•International Journal of Head and Neck SurgeryOpen access

Correlation of Parotid Gland Function in Head and Neck Cancer Patients treated with Intensity-modulated Radiotherapy

Sonal Vahanwala, Sukhjinder Kaur Khosa, Sandeep Pagare

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Abstract

ABSTRACT Xerostomia is one of the most common side effects after radiation therapy for treating head and neck cancers. Our objective was to evaluate the salivary flow in patients treated with Intensity-modulated radiotherapy with two samples: (a) Resting saliva and (b) stimulated saliva. We performed three salivary sample collections: At the beginning, during and immediately after radiotherapy. The results showed that there was a significant decrease in the whole resting (11.46%) and stimulated (15.06%) salivary flow values during the first 3 weeks of the radiotherapy (p = 0.0025, p = 0.0034 respectively). How to cite this article Khosa SK, Vahanwala S, Pagare SS. Correlation of Parotid Gland Function in Head and Neck Cancer Patients treated with Intensity-modulated Radiotherapy. Int J Head and Neck Surg 2012;3(1):1-4.

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ABSTRACT Xerostomia is one of the most common side effects after radiation therapy for treating head and neck cancers. Our objective was to evaluate the salivary flow in patients treated with Intensity-modulated radiotherapy with two samples: (a) Resting saliva and (b) stimulated saliva. We performed three salivary sample collections: At the beginning, during and immediately after radiotherapy. The results showed that there was a significant decrease in the whole resting (11.46%) and stimulated (15.06%) salivary flow values during the first 3 weeks of the radiotherapy (p = 0.0025, p = 0.0034 respectively). How to cite this article Khosa SK, Vahanwala S, Pagare SS. Correlation of Parotid Gland Function in Head and Neck Cancer Patients treated with Intensity-modulated Radiotherapy. Int J Head and Neck Surg 2012;3(1):1-4.

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Available abstract

ABSTRACT Xerostomia is one of the most common side effects after radiation therapy for treating head and neck cancers. Our objective was to evaluate the salivary flow in patients treated with Intensity-modulated radiotherapy with two samples: (a) Resting saliva and (b) stimulated saliva. We performed three salivary sample collections: At the beginning, during and immediately after radiotherapy. The results showed that there was a significant decrease in the whole resting (11.46%) and stimulated (15.06%) salivary flow values during the first 3 weeks of the radiotherapy (p = 0.0025, p = 0.0034 respectively). How to cite this article Khosa SK, Vahanwala S, Pagare SS. Correlation of Parotid Gland Function in Head and Neck Cancer Patients treated with Intensity-modulated Radiotherapy. Int J Head and Neck Surg 2012;3(1):1-4.

Key concepts: Medicine, Radiation therapy, Head and neck cancer, Saliva, Head and neck, Parotid gland, Salivary gland, Cancer

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