2004•Drug Metabolism and DispositionRequires access

INDUCTION AND INHIBITION OF CYTOCHROMES P450 BY THE ST. JOHN’S WORT CONSTITUENT HYPERFORIN IN HUMAN HEPATOCYTE CULTURES

Bernard J. Komoroski, Shimin Zhang, Hongbo Cai, James Matthew Hutzler, Reginald F. Frye, Timothy S. Tracy, Stephen C. Strom, Thomas J. Lehmann, CATHARINA Y. W. ANG, Yan Cui, Raman Venkataramanan

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Key concepts: Hyperforin, Hypericum perforatum, CYP3A4, Hypericin, CYP1A2, Pharmacology, Grapefruit juice, Cytochrome P450

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INDUCTION AND INHIBITION OF CYTOCHROMES P450 BY THE ST. JOHN’S WORT CONSTITUENT HYPERFORIN IN HUMAN HEPATOCYTE CULTURES — Research Paper | ScholarLens