2011•Journal of Thoracic and Cardiovascular SurgeryOpen access

Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature

William M. Yarbrough, Rupak Mukherjee, Robert E. Stroud, William T. Rivers, J. Marshall Oelsen, Jennifer A. Dixon, Shaina R. Eckhouse, John S. Ikonomidis, Michael R. Zile, Francis G. Spinale

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Key concepts: Pressure overload, Medicine, Cardiology, Internal medicine, Ejection fraction, Ventricular pressure, Ventricular remodeling, Extracellular matrix