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Screening of Benzoylecgonine in Urine by Cyclobond Solid Phase Extraction and High Performance TLC

Joseph Sherma, Joseph E. Bernardo, Matthew H. Higgs

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Abstract

A method is described for screening of the cocaine metabolite benzoylecgonine in urine at 0.2 μ/ml using a Cyclobond cyclodex−trin solid phase extraction cartridge and high performance thin layer chromatography. Results are compared with those obtained using liquid-liquid and diatomaceous earth column extraction and C-18 solid phase extraction.

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What this paper is about

A method is described for screening of the cocaine metabolite benzoylecgonine in urine at 0.2 μ/ml using a Cyclobond cyclodex−trin solid phase extraction cartridge and high performance thin layer chromatography. Results are compared with those obtained using liquid-liquid and diatomaceous earth column extraction and C-18 solid phase extraction.

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Available abstract

A method is described for screening of the cocaine metabolite benzoylecgonine in urine at 0.2 μ/ml using a Cyclobond cyclodex−trin solid phase extraction cartridge and high performance thin layer chromatography. Results are compared with those obtained using liquid-liquid and diatomaceous earth column extraction and C-18 solid phase extraction.

Key concepts: Benzoylecgonine, Chromatography, Solid phase extraction, Extraction (chemistry), Urine, Cartridge, Metabolite, Chemistry

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