2014•Nucleic Acids ResearchOpen access

A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip

Hitoshi Hiura, Atsushi Sugawara, Hidehiko Ogawa, Rosalind M. John, Naoko Miyauchi, Yusuke Miyanari, Takumi Horiike, Yufeng Li, Nobuo Yaegashi, Hiroyuki Sasaki, Tomohiro Kono, T. Arima

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Abstract

Nucl. Acids Res. (2010) 38 (15): 4929-4945. doi:10.1093/nar/gkq200 Editorial Expression of Concern The Editors express a note of concern regarding the article “A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip “ by Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, and Arima T, which was published in issue 15, volume 38 (2010) of Nucleic Acids Research. The Editors wish to alert the readers that questions have been raised about the validity of some of the figures presented in this article. The Editors note that Figures 2, 4, 6 and S3 contain duplicate panels. New figures are available in the Supplementary Data accompanying this expression of concern. Having reviewed the original data, we believe that the results and conclusion of the article are valid but wish to alert our readership to these concerns. Keith Fox Barry Stoddard Senior Executive Editors Nucleic Acids Research

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Nucl. Acids Res. (2010) 38 (15): 4929-4945. doi:10.1093/nar/gkq200 Editorial Expression of Concern The Editors express a note of concern regarding the article “A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip “ by Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, and Arima T, which was published in issue 15, volume 38 (2010) of Nucleic Acids Research. The Editors wish to alert the readers that questions have been raised about the validity of some of the figures presented in this article. The Editors note that Figures 2, 4, 6 and S3 contain duplicate panels. New figures are available in the Supplementary Data accompanying this expression of concern. Having reviewed the original data, we believe that the results and conclusion of the article are valid but wish to alert our readership to these concerns. Keith Fox Barry Stoddard Senior Executive Editors Nucleic Acids Research

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Available abstract

Nucl. Acids Res. (2010) 38 (15): 4929-4945. doi:10.1093/nar/gkq200 Editorial Expression of Concern The Editors express a note of concern regarding the article “A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip “ by Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, and Arima T, which was published in issue 15, volume 38 (2010) of Nucleic Acids Research. The Editors wish to alert the readers that questions have been raised about the validity of some of the figures presented in this article. The Editors note that Figures 2, 4, 6 and S3 contain duplicate panels. New figures are available in the Supplementary Data accompanying this expression of concern. Having reviewed the original data, we believe that the results and conclusion of the article are valid but wish to alert our readership to these concerns. Keith Fox Barry Stoddard Senior Executive Editors Nucleic Acids Research

Key concepts: Methylated DNA immunoprecipitation, Differentially methylated regions, Biology, Genomic imprinting, DNA methylation, Methylation, Molecular biology, Genetics

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