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Counterimmunoelectrophoresis in the diagnosis of mycetoma and its sensitivity as compared to immunodiffusion

S.A. Gumaa, El Sheikh Mahgoub

Abstract

Counterimmunoelectrophoresis used for the diagnosis of mycetoma was found superior to immunodiffusion (ID) especially when using neat serum and 1:2 dilution (P=less than 0.0001 with neat serum; and less than 0.01 with 1:2 dilution). It is recommended for routine use in mycology laboratories for following up patients on treatment and for confirming the diagnosis of sera that are weakly positive by ID.

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Available abstract

Key concepts: Counterimmunoelectrophoresis, Immunodiffusion, Mycetoma, Ouchterlony double immunodiffusion, Medicine, Immunoelectrophoresis, Microbiology, Immunology