Solid‐Phase Synthesis of Natural Products and Natural Product‐Like Libraries
K. C. Nicolaou, Jeffrey A. Pfefferkorn
Abstract
K. C. Nicolaou, Jeffrey A. Pfefferkorn
Abstract
This chapter contains sections titled: Introduction Solid-phase Derivatization of Natural Product Scaffolds – Combinatorial Semisynthesis Solid-phase Semisynthesis of Rauwolfa Alkaloids Solid-phase Synthesis of Purine Derivatives Solid-phase Semisynthesis of a Taxoid Library Solid-phase Semisynthesis of Sarcodictyns A and B and Libraries Thereof Solid-phase Semisynthesis of Vancomycin Solid-phase Total Synthesis of Natural Products – Combinatorial Total Synthesis Solid-phase Synthesis of Prostaglandins and Libraries Thereof Solid-phase Synthesis of Epothilone A and Libraries Thereof Solid-phase Synthesis of (S)-Zearalenone Solid-phase Synthesis of (DL)-Muscone and Libraries Thereof Solid-phase Synthesis of the Vitamin D3 System Solid-phase Synthesis of Carpanone-like Molecules Combinatorial Solid-phase Synthesis of Natural Product-like Libraries Conclusion Addendum References
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This chapter contains sections titled: Introduction Solid-phase Derivatization of Natural Product Scaffolds – Combinatorial Semisynthesis Solid-phase Semisynthesis of Rauwolfa Alkaloids Solid-phase Synthesis of Purine Derivatives Solid-phase Semisynthesis of a Taxoid Library Solid-phase Semisynthesis of Sarcodictyns A and B and Libraries Thereof Solid-phase Semisynthesis of Vancomycin Solid-phase Total Synthesis of Natural Products – Combinatorial Total Synthesis Solid-phase Synthesis of Prostaglandins and Libraries Thereof Solid-phase Synthesis of Epothilone A and Libraries Thereof Solid-phase Synthesis of (S)-Zearalenone Solid-phase Synthesis of (DL)-Muscone and Libraries Thereof Solid-phase Synthesis of the Vitamin D3 System Solid-phase Synthesis of Carpanone-like Molecules Combinatorial Solid-phase Synthesis of Natural Product-like Libraries Conclusion Addendum References
Key concepts: Semisynthesis, Solid-phase synthesis, Natural product, Chemistry, Phase (matter), Combinatorial chemistry, Organic chemistry, Biochemistry