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2009•Chemical CommunicationsOpen access

“Clickable” elastins: elastin-like polypeptides functionalized with azide or alkyne groups

Rosalie L. M. Teeuwen, Sander S. van Berkel, Tim H. H. van Dulmen, Sanne Schoffelen, Silvie A. Meeuwissen, Han Zuilhof, Frits A. de Wolf, Jan C. M. van Hest

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Abstract

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide-alkyne cycloaddition to a variety of (bio)molecules.

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What this paper is about

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide-alkyne cycloaddition to a variety of (bio)molecules.

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OpenAlex reports 48 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide-alkyne cycloaddition to a variety of (bio)molecules.

Key concepts: Alkyne, Azide, Elastin, Cycloaddition, Chemistry, Combinatorial chemistry, Molecule, Organic chemistry

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