Methods and models to study irrigation

The success of endodontic treatment depends on the eradication of microbes from the root canal system and prevention of reinfection. The factors that remain a challenge in the irrigation and disinfection of the root canal include biofilm resistance, poor penetration of the irrigant, and exchange of irrigants in the highly complex root canal anatomy. Progress in the search for better irrigants and irrigant delivery is necessary. A variety of different study models have been used in endodontic research on irrigation. In this article, the various models are discussed in light of relevant literature.