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1963•Transactions of the Royal Society of Tropical Medicine and HygieneRequires access

Malabsorption of vitamin B12 in megaloblastic anaemia among Africans and Indians in Durban

W Hift, E. B. Adams

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Abstract

The absorption of radioactive vitamin B12 was investigated in 16 African and Indian patients with megaloblastic anaemia due to folic acid deficiency. The mean urinary excretion (6.5 per cent.) was poor compared with a control group of patients with iron-deficiency anaemia (mean 20.3 per cent.). Serial tests showed that definite vitamin B12 malabsorption was persistent in three patients, while in two others it was temporary, corrected by treatment.

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What this paper is about

The absorption of radioactive vitamin B12 was investigated in 16 African and Indian patients with megaloblastic anaemia due to folic acid deficiency. The mean urinary excretion (6.5 per cent.) was poor compared with a control group of patients with iron-deficiency anaemia (mean 20.3 per cent.). Serial tests showed that definite vitamin B12 malabsorption was persistent in three patients, while in two others it was temporary, corrected by treatment.

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OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The absorption of radioactive vitamin B12 was investigated in 16 African and Indian patients with megaloblastic anaemia due to folic acid deficiency. The mean urinary excretion (6.5 per cent.) was poor compared with a control group of patients with iron-deficiency anaemia (mean 20.3 per cent.). Serial tests showed that definite vitamin B12 malabsorption was persistent in three patients, while in two others it was temporary, corrected by treatment.

Key concepts: Malabsorption, Megaloblastic anaemia, Vitamin B12, Gastroenterology, Excretion, Folic acid, Internal medicine, Cyanocobalamin

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