2007•Clinical PediatricsRequires access

Serum Zinc Levels in Children With Simple Febrile Seizure

Ramaswamy Ganesh, Lalitha Janakiraman

Abstract

A prospective case-control study was conducted in a major tertiary care hospital for children during June 2005 to May 2006 on children aged between 3 months and 5 years to compare serum zinc levels in 38 cases of simple febrile seizure and 38 age-matched controls. The mean serum zinc levels in cases and controls were 32.17 and 87.6 microg/dL, respectively. This difference was statistically significant ( P < .001). We conclude that Indian children with febrile seizure had low serum zinc levels, and zinc supplementation to reduce the incidence of febrile seizure should be investigated.

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Key concepts: Medicine, Incidence (geometry), Zinc, Febrile seizure, Pediatrics, Prospective cohort study, Case-control study, Zinc deficiency (plant disorder)