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2002•Infection and ImmunityOpen access

Novel Laminin-Binding Protein of Streptococcus pyogenes , Lbp, Is Involved in Adhesion to Epithelial Cells

Yutaka Terao, Shigetada Kawabata, Eiji Kunitomo, Ichirô Nakagawa, Shigeyuki Hamada

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Abstract

The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significantly lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins.

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What this paper is about

The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significantly lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins.

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Available abstract

The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significantly lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins.

Key concepts: Streptococcus pyogenes, Bacterial adhesin, Biology, Laminin, Microbiology, Adhesion, Mutant, Gene

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Novel Laminin-Binding Protein of Streptococcus pyogenes , Lbp, Is Involved in Adhesion to Epithelial Cells — Research Paper | ScholarLens