2013•Canadian Medical Association JournalOpen access

Treating Clostridium difficile infection

Daniel M. Shafran, Stephen D. Shafran

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Abstract

A randomized controlled trial (RCT) showed that metronidazole was as effective as vancomycin taken orally for the treatment of mild Clostridium difficile infection. However, in cases of severe infection, 97% of patients given vancomycin had clinical resolution compared with only 76% of those given

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A randomized controlled trial (RCT) showed that metronidazole was as effective as vancomycin taken orally for the treatment of mild Clostridium difficile infection. However, in cases of severe infection, 97% of patients given vancomycin had clinical resolution compared with only 76% of those given

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Available abstract

A randomized controlled trial (RCT) showed that metronidazole was as effective as vancomycin taken orally for the treatment of mild Clostridium difficile infection. However, in cases of severe infection, 97% of patients given vancomycin had clinical resolution compared with only 76% of those given

Key concepts: Metronidazole, Clostridium difficile, Vancomycin, Medicine, Randomized controlled trial, Clostridium, Clostridium Infections, Microbiology

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