Effectiveness of terbinafine in the eradication ofMicrosporum canisfrom laboratory cats
Laura Rocío Castañón-Olivares, Patricia Manzano–Gayosso, R. López‐Martínez, Inti A. De La Rosa-Velázquez, E. Soto‐Reyes‐Solís
Abstract
Laura Rocío Castañón-Olivares, Patricia Manzano–Gayosso, R. López‐Martínez, Inti A. De La Rosa-Velázquez, E. Soto‐Reyes‐Solís
Abstract
In this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by Microsporum canis, which was isolated in 45% of cases. All cats were treated with oral terbinafine for 3 weeks. The drug was administered orally at a daily dosage 8.25 mg kg-1. Mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. The final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demonstrating that terbinafine is an effective method of eradication of dermatophyte colonization.
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In this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by Microsporum canis, which was isolated in 45% of cases. All cats were treated with oral terbinafine for 3 weeks. The drug was administered orally at a daily dosage 8.25 mg kg-1. Mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. The final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demonstrating that terbinafine is an effective method of eradication of dermatophyte colonization.
Key concepts: Microsporum canis, Terbinafine, CATS, Microsporum, Microbiology, Medicine, Biology, Virology