Quantum Dots as a Novel Immunofluorescent Detection System for Cryptosporidium parvum and Giardia lamblia
Liang Zhu, Simon S. Ang, Wen‐Tso Liu
Abstract
Liang Zhu, Simon S. Ang, Wen‐Tso Liu
Abstract
Semiconductor quantum dot-conjugated antibodies were successfully developed to label Cryptosporidium parvum and Giardia lamblia. This novel fluorescence system exhibited superior photostability, gave 1.5- to 9-fold-higher signal-to-noise ratios than traditional organic dyes in detecting C. parvum, and allowed dual-color detection for C. parvum and G. lamblia.
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Semiconductor quantum dot-conjugated antibodies were successfully developed to label Cryptosporidium parvum and Giardia lamblia. This novel fluorescence system exhibited superior photostability, gave 1.5- to 9-fold-higher signal-to-noise ratios than traditional organic dyes in detecting C. parvum, and allowed dual-color detection for C. parvum and G. lamblia.
Key concepts: Giardia lamblia, Cryptosporidium parvum, Cryptosporidium, Giardia, Quantum dot, Fluorescence, Protozoa, Microbiology