2004•Nature Structural & Molecular BiologyOpen access

The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

Shang‐Te Danny Hsu, Eefjan Breukink, Eugene Tischenko, Mandy Lutters, Ben de Kruijff, Robert Kaptein, Alexandre M. J. J. Bonvin, Nico A. J. van Nuland

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Key concepts: Lipid II, Lantibiotics, Nisin, Lanthionine, Chemistry, Biochemistry, Pyrophosphate, Antimicrobial peptides

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