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Circadian rhythm in humans

Klemen Španinger, Rok Košir, Martina Fink, Nataša Debeljak, Damjana Rozman

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Abstract

Background: Chronobiology is a field of science that examines periodic (cyclic) phenomena in living organisms and their adaptation to solar and lunar related rhythms. These rhythms have frequencies lasting from milliseconds to years. Some biological rhythms depend on the events in the environment. Th ese include alternations of day and night, changes in environment temperature and changes of seasons. Research in the last few years showed the importance of biological rhythms for the human health and well being. Th e most widely investigated biological rhythm is the circadian rhythm which has a period of approximately 24 h. Conclusions: Chronobiology and chronomedicine are becoming important fields in understanding the functions of the human body. Another emerging field of science is chronopharmacology whose main objective is to elucidate the time points at which drugs will be most effective and will have the least side effects.

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What this paper is about

Background: Chronobiology is a field of science that examines periodic (cyclic) phenomena in living organisms and their adaptation to solar and lunar related rhythms. These rhythms have frequencies lasting from milliseconds to years. Some biological rhythms depend on the events in the environment. Th ese include alternations of day and night, changes in environment temperature and changes of seasons. Research in the last few years showed the importance of biological rhythms for the human health and well being. Th e most widely investigated biological rhythm is the circadian rhythm which has a period of approximately 24 h. Conclusions: Chronobiology and chronomedicine are becoming important fields in understanding the functions of the human body. Another emerging field of science is chronopharmacology whose main objective is to elucidate the time points at which drugs will be most effective and will have the least side effects.

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Available abstract

Background: Chronobiology is a field of science that examines periodic (cyclic) phenomena in living organisms and their adaptation to solar and lunar related rhythms. These rhythms have frequencies lasting from milliseconds to years. Some biological rhythms depend on the events in the environment. Th ese include alternations of day and night, changes in environment temperature and changes of seasons. Research in the last few years showed the importance of biological rhythms for the human health and well being. Th e most widely investigated biological rhythm is the circadian rhythm which has a period of approximately 24 h. Conclusions: Chronobiology and chronomedicine are becoming important fields in understanding the functions of the human body. Another emerging field of science is chronopharmacology whose main objective is to elucidate the time points at which drugs will be most effective and will have the least side effects.

Key concepts: Circadian rhythm, Rhythm, Infradian rhythm, Phase response curve, Biology, Neuroscience, Ultradian rhythm, Medicine

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