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2005•Antimicrobial Agents and ChemotherapyOpen access

Sublethal Concentrations of Ciprofloxacin Induce Bacteriocin Synthesis in Escherichia coli

Borut Jerman, Matej Butala, Darja Žgur‐Bertok

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Abstract

Antibiotics that interfere with DNA replication, as well as cell wall synthesis, induce the SOS response. In this report, we show that ciprofloxacin induces synthesis of colicins, narrow-spectrum antibiotics frequently produced by Escherichia coli strains, in an SOS-dependent manner.

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What this paper is about

Antibiotics that interfere with DNA replication, as well as cell wall synthesis, induce the SOS response. In this report, we show that ciprofloxacin induces synthesis of colicins, narrow-spectrum antibiotics frequently produced by Escherichia coli strains, in an SOS-dependent manner.

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OpenAlex reports 39 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Antibiotics that interfere with DNA replication, as well as cell wall synthesis, induce the SOS response. In this report, we show that ciprofloxacin induces synthesis of colicins, narrow-spectrum antibiotics frequently produced by Escherichia coli strains, in an SOS-dependent manner.

Key concepts: Escherichia coli, Colicin, Ciprofloxacin, Bacteriocin, SOS response, Antibiotics, Microbiology, Enterobacteriaceae

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