2013•Cellular SignallingRequires access

β-Catenin-dependent pathway activation by both promiscuous “canonical” WNT3a–, and specific “noncanonical” WNT4– and WNT5a–FZD receptor combinations with strong differences in LRP5 and LRP6 dependency

Larisa Ring, Peter Neth, Christian Weber, Sabine Steffens, Alexander Faußner

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Key concepts: LRP5, LRP6, Wnt signaling pathway, Frizzled, WNT3A, WNT4, Cell biology, Dishevelled

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β-Catenin-dependent pathway activation by both promiscuous “canonical” WNT3a–, and specific “noncanonical” WNT4– and WNT5a–FZD receptor combinations with strong differences in LRP5 and LRP6 dependency — Research Paper | ScholarLens