Double‐blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis.
Butler Rc, D.L.H. Goddard, CS Higgens, P. Hollingworth, CT Pease, M. A. Stodell, JT Scott
Abstract
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Butler Rc, D.L.H. Goddard, CS Higgens, P. Hollingworth, CT Pease, M. A. Stodell, JT Scott
Abstract
Open-access reader
Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout. Patients received either flurbiprofen 400 mg daily for 48 h followed by 200 mg daily, or phenylbutazone 800 mg daily for 48 h followed by 400 mg daily. The drugs were of comparable efficacy, while side-effects were uncommon and relatively mild. Flurbiprofen appears to be a satisfactory alternative to phenylbutazone in the management of acute gouty arthritis.
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Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout. Patients received either flurbiprofen 400 mg daily for 48 h followed by 200 mg daily, or phenylbutazone 800 mg daily for 48 h followed by 400 mg daily. The drugs were of comparable efficacy, while side-effects were uncommon and relatively mild. Flurbiprofen appears to be a satisfactory alternative to phenylbutazone in the management of acute gouty arthritis.
Key concepts: Phenylbutazone, Flurbiprofen, Medicine, Gout, Arthritis, Double blind, Gouty arthritis, Internal medicine