2007•The Journal of Organic ChemistryRequires access

Simple Glycosylation Reaction of Allyl Glycosides

Pengfei Wang, Pranab Haldar, Yun Wang, Huayou Hu

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Abstract

A simple glycosylation strategy employing only allyl glycosides is described. In a one-pot fashion, an allyl glycoside is first isomerized to the reactive 1-prop-en-yl glycoside intermediate, which subsequently undergoes glycosylation with a glycosyl acceptor, promoted by NIS at room temperature.

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A simple glycosylation strategy employing only allyl glycosides is described. In a one-pot fashion, an allyl glycoside is first isomerized to the reactive 1-prop-en-yl glycoside intermediate, which subsequently undergoes glycosylation with a glycosyl acceptor, promoted by NIS at room temperature.

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Available abstract

A simple glycosylation strategy employing only allyl glycosides is described. In a one-pot fashion, an allyl glycoside is first isomerized to the reactive 1-prop-en-yl glycoside intermediate, which subsequently undergoes glycosylation with a glycosyl acceptor, promoted by NIS at room temperature.

Key concepts: Chemistry, Glycosylation, Glycoside, Glycosyl, Glycosyl donor, Acceptor, Stereochemistry, Organic chemistry

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