Mutants of the Arginine-proline Pathway in Aspergillus Nidulans
Małgorzata Piotrowska, Marek Sawicki, Piotr Węgleński
Abstract
Małgorzata Piotrowska, Marek Sawicki, Piotr Węgleński
Abstract
Summary: Proline suppressor mutant su-19 was analysed for arginase and ornithine δ-transaminase (OTA) activity. Both enzymes are constitutively produced by this mutant. Five other suppressor loci not linked with su-19 or to each other are involved in regulation of the two enzymes. A mutant showing no OTA activity was isolated. Properties of this mutant and its effect in various strains of the pro su type were studied.
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Summary: Proline suppressor mutant su-19 was analysed for arginase and ornithine δ-transaminase (OTA) activity. Both enzymes are constitutively produced by this mutant. Five other suppressor loci not linked with su-19 or to each other are involved in regulation of the two enzymes. A mutant showing no OTA activity was isolated. Properties of this mutant and its effect in various strains of the pro su type were studied.
Key concepts: Aspergillus nidulans, Mutant, Arginase, Proline, Arginine, Ornithine, Suppressor, Enzyme