1974•Journal of Clinical InvestigationOpen access

Regulation of Human Lipolysis IN VIVO OBSERVATIONS ON THE ROLE OF ADRENERGIC RECEPTORS

Thomas W. Burns, James M. Mohs, Paul E. Langley, Roy A. Yawn, Gerald R. Chase

Abstract

Changes in the plasma free fatty acids of a pancreatectomized subject and in free fatty acids and insulin in 10 normal subjects in response to the in vivo infusion of epinephrine alone, epinephrine plus phentolamine, and epinephrine plus propranolol indicate that both alpha and beta adrenergic receptors are present in human adipose tissue. Under the experimental conditions used, adipose tissue appeared to be more responsive to epinephrine than did the cardiovascular system.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 28 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Phentolamine, Lipolysis, Epinephrine, Adipose tissue, Endocrinology, Propranolol, Internal medicine, Adrenergic receptor