1998•Drug Development and Industrial PharmacyRequires access

Theoretical Approaches and Practical Investigations in Carbopol Buccal Patches for Drug Delivery

Jian‐Hwa Guo, K. M. Cooklock

Abstract

This paper describes the theoretical approaches in the peeling test method which can be used to evaluate the bioadhesive patches for buccal drug delivery purposes. The effects of patch thickness and the peeling rate on the bioadhesion of buccal patches were investigated from a theoretical point of view. The influence of a crosslinking agent on the swelling and bioadhesive properties of the patches was also evaluated.

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Available abstract

Key concepts: Bioadhesive, Buccal administration, Drug delivery, Swelling, Dosage form, Biomedical engineering, Nanotechnology, Chemistry