2007•Journal of Clinical MicrobiologyOpen access

Systematic Survey of Nonspecific Agglutination by Candida spp. in Latex Assays

Karsten Becker, Ahmed S. Almasri, Christof von Eiff, Georg Peters, Christine Heilmann, W. Fegeler

Abstract

In order to demonstrate that cells of Candida spp. may show considerable nonspecific agglutination in latex agglutination tests, 150 clinical and reference isolates of 12 yeast species were systematically studied by applying various test parameters. In fact, 40 (26.7%) of these isolates revealed nonspecific results, significantly associated with the time allowed for agglutination.

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Key concepts: Latex fixation test, Agglutination (biology), Microbiology, Direct agglutination test, Biology, Candida infections, Yeast, Immunology