ADJUVANT TRAZODONE IN THE TREATMENT OF ALCOHOLISM: AN OPEN STUDY
Luigi Janiri, A. Hadjichristos, Andrés Buonanno, Roberto Rago, Paolo Mannelli, Sergio De Risio
Abstract
Luigi Janiri, A. Hadjichristos, Andrés Buonanno, Roberto Rago, Paolo Mannelli, Sergio De Risio
Abstract
Serotonergic drugs have been proven to be helpful to alcoholics in maintaining abstinence. In this open study, we report that the atypical antidepressant trazodone at low doses was able to significantly decrease craving for alcohol, depressive, and anxious symptoms in a number (25) of detoxified alcohol-dependent subjects after 3 months of treatment. Trazodone may, therefore, be an adjuvant in the therapy of alcoholism.
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Serotonergic drugs have been proven to be helpful to alcoholics in maintaining abstinence. In this open study, we report that the atypical antidepressant trazodone at low doses was able to significantly decrease craving for alcohol, depressive, and anxious symptoms in a number (25) of detoxified alcohol-dependent subjects after 3 months of treatment. Trazodone may, therefore, be an adjuvant in the therapy of alcoholism.
Key concepts: Trazodone, Adjuvant, Medicine, Psychiatry, Internal medicine, Antidepressant, Anxiety