2015Journal of Orthopaedic Surgery and ResearchOpen access

Retraction Note: A meta-analysis of external fixator versus intramedullary nails for open tibial fracture fixation

Xian Xu, Xu Li, Lin Liu, Wei Wu

Open full text 0 citations

Abstract

To compare the clinical outcomes of external fixator (EF) and intramedullary nails (IN) in the treatment of open tibial fractures. We searched seven electronic databases (PubMed, MEDLINE, EMBASE, OVID, Cochrane library, CNKI, and CBM) for trials of tibial fracture fixation published from 1980 to 2013. The indicators including postoperative infection, malunion, nonunion, soft tissue injury, delayed healing, and healing time were used for quantitative outcome assessments. A total of nine trials involving 532 patients (EF, n = 253; IN, n = 279) with open tibia fractures were included in this meta-analysis. The results indicated that the patients undergoing IN had lower incidence of postoperative infection (risk radio [RR] = 3.85; 95% confidence intervals [CI], 2.67–5.54; P < 0.0001), malunion (RR = 2.31; 95% CI, 1.40–3.81; P = 0.001), nonunion (RR = 1.41; 95% CI, 1.06–1.88; P = 0.02) and less healing time (weighted mean difference [WMD] = 6.19; 95% CI, 1.42–10.96; P = 0.01) compared with EF. However, regarding to the soft tissue injury (RR = 0.74; 95% CI, 0.34–1.62; P = 0.45) and delayed healing (RR = 1.38; 95% CI, 0.79–2.43; P = 0.26), there is no significantly difference between EF and IN approach. In conclusion, the use of IN is more effective than EF and may be considered as first-line approach in fixation of open tibial fractures.

Open-access reader

About this research paper

What this paper is about

To compare the clinical outcomes of external fixator (EF) and intramedullary nails (IN) in the treatment of open tibial fractures. We searched seven electronic databases (PubMed, MEDLINE, EMBASE, OVID, Cochrane library, CNKI, and CBM) for trials of tibial fracture fixation published from 1980 to 2013. The indicators including postoperative infection, malunion, nonunion, soft tissue injury, delayed healing, and healing time were used for quantitative outcome assessments. A total of nine trials involving 532 patients (EF, n = 253; IN, n = 279) with open tibia fractures were included in this meta-analysis. The results indicated that the patients undergoing IN had lower incidence of postoperative infection (risk radio [RR] = 3.85; 95% confidence intervals [CI], 2.67–5.54; P < 0.0001), malunion (RR = 2.31; 95% CI, 1.40–3.81; P = 0.001), nonunion (RR = 1.41; 95% CI, 1.06–1.88; P = 0.02) and less healing time (weighted mean difference [WMD] = 6.19; 95% CI, 1.42–10.96; P = 0.01) compared with EF. However, regarding to the soft tissue injury (RR = 0.74; 95% CI, 0.34–1.62; P = 0.45) and delayed healing (RR = 1.38; 95% CI, 0.79–2.43; P = 0.26), there is no significantly difference between EF and IN approach. In conclusion, the use of IN is more effective than EF and may be considered as first-line approach in fixation of open tibial fractures.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

To compare the clinical outcomes of external fixator (EF) and intramedullary nails (IN) in the treatment of open tibial fractures. We searched seven electronic databases (PubMed, MEDLINE, EMBASE, OVID, Cochrane library, CNKI, and CBM) for trials of tibial fracture fixation published from 1980 to 2013. The indicators including postoperative infection, malunion, nonunion, soft tissue injury, delayed healing, and healing time were used for quantitative outcome assessments. A total of nine trials involving 532 patients (EF, n = 253; IN, n = 279) with open tibia fractures were included in this meta-analysis. The results indicated that the patients undergoing IN had lower incidence of postoperative infection (risk radio [RR] = 3.85; 95% confidence intervals [CI], 2.67–5.54; P < 0.0001), malunion (RR = 2.31; 95% CI, 1.40–3.81; P = 0.001), nonunion (RR = 1.41; 95% CI, 1.06–1.88; P = 0.02) and less healing time (weighted mean difference [WMD] = 6.19; 95% CI, 1.42–10.96; P = 0.01) compared with EF. However, regarding to the soft tissue injury (RR = 0.74; 95% CI, 0.34–1.62; P = 0.45) and delayed healing (RR = 1.38; 95% CI, 0.79–2.43; P = 0.26), there is no significantly difference between EF and IN approach. In conclusion, the use of IN is more effective than EF and may be considered as first-line approach in fixation of open tibial fractures.

Key concepts: Medicine, Intramedullary rod, External fixator, Orthopedic surgery, Open fracture, External fixation, Tibial fracture, Fixation (population genetics)

Related papers

Back to paper searchBrowse research topicsOriginal source
Retraction Note: A meta-analysis of external fixator versus intramedullary nails for open tibial fracture fixation — Research Paper | ScholarLens