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1971•The Journal of AntibioticsOpen access

TETRAMYCIN, A NEW POLYENE ANTIBIOTIC

K. Dornberger, Rosemarie Fügner, Gertraud Bradler, H. Thrum

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Abstract

A new polyene antibiotic was isolated from the culture broth of a new Streptomyces, designated as Streptomyces noursei HAZEN et BROWN, 1950 var. jenensis nov. var. JA 3789. This antibiotic is a tetraene and was named tetramycin. The morphological and physiological characteristics of Streptomyces JA 3789 and the isolation, purification, physiochemical, and biological properties of the antibiotic are described. Tetramycin was differentiated from related antibiotics by physical and chemical data.

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A new polyene antibiotic was isolated from the culture broth of a new Streptomyces, designated as Streptomyces noursei HAZEN et BROWN, 1950 var. jenensis nov. var. JA 3789. This antibiotic is a tetraene and was named tetramycin. The morphological and physiological characteristics of Streptomyces JA 3789 and the isolation, purification, physiochemical, and biological properties of the antibiotic are described. Tetramycin was differentiated from related antibiotics by physical and chemical data.

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Available abstract

A new polyene antibiotic was isolated from the culture broth of a new Streptomyces, designated as Streptomyces noursei HAZEN et BROWN, 1950 var. jenensis nov. var. JA 3789. This antibiotic is a tetraene and was named tetramycin. The morphological and physiological characteristics of Streptomyces JA 3789 and the isolation, purification, physiochemical, and biological properties of the antibiotic are described. Tetramycin was differentiated from related antibiotics by physical and chemical data.

Key concepts: Polyene, Antibiotics, Streptomyces, Isolation (microbiology), Microbiology, Streptomycetaceae, Actinomycetales, Chemistry

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