2013Turkish Journal of BiochemistryRequires access

Complete Blood Cell Parameters between Anti-HP IgG Antibody Positive and Negative Subjects

Tevfik Noyan

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Abstract

Objective: The aim of this study was to determine whether there is any difference in complete blood cell count parameters between anti-Helicobacter pylori (HP) IgG antibody (anti-IgG) positive and negative subjects. Methods: In a hospital based survey, total of 125 people were included to the study which measured anti-HP IgG antibody. The total 85 subjects, titers of anti-HP IgG antibody > 1 was considered as IgG positive group and <1, total 40 subjects, as IgG negative group. Results: There was no significant relationship between anti-HP IgG antibody positivity and gender. However, significantly decreased mean corpuscular volume and increased percent eosinophil values were found in IgG positive group (p =0.04). Conclusion: In conclusion, IgG positive group characterized lower mean corpuscular volume and higher eosinophil values. These results might be sign of inflammatory changes associated to chronic gastritis.

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Objective: The aim of this study was to determine whether there is any difference in complete blood cell count parameters between anti-Helicobacter pylori (HP) IgG antibody (anti-IgG) positive and negative subjects. Methods: In a hospital based survey, total of 125 people were included to the study which measured anti-HP IgG antibody. The total 85 subjects, titers of anti-HP IgG antibody > 1 was considered as IgG positive group and <1, total 40 subjects, as IgG negative group. Results: There was no significant relationship between anti-HP IgG antibody positivity and gender. However, significantly decreased mean corpuscular volume and increased percent eosinophil values were found in IgG positive group (p =0.04). Conclusion: In conclusion, IgG positive group characterized lower mean corpuscular volume and higher eosinophil values. These results might be sign of inflammatory changes associated to chronic gastritis.

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Available abstract

Objective: The aim of this study was to determine whether there is any difference in complete blood cell count parameters between anti-Helicobacter pylori (HP) IgG antibody (anti-IgG) positive and negative subjects. Methods: In a hospital based survey, total of 125 people were included to the study which measured anti-HP IgG antibody. The total 85 subjects, titers of anti-HP IgG antibody > 1 was considered as IgG positive group and <1, total 40 subjects, as IgG negative group. Results: There was no significant relationship between anti-HP IgG antibody positivity and gender. However, significantly decreased mean corpuscular volume and increased percent eosinophil values were found in IgG positive group (p =0.04). Conclusion: In conclusion, IgG positive group characterized lower mean corpuscular volume and higher eosinophil values. These results might be sign of inflammatory changes associated to chronic gastritis.

Key concepts: Antibody, Immunology, Medicine

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