2015•Cancer CellRequires access

Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes

Ana Herrero, Adán Pinto, Paula Colón‐Bolea, Berta Casar, Mary Alice Jones, Lorena Agudo‐Ibáñez, Rebeca Vidal, Stephan P. Tenbaum, Paolo Nucíforo, Elsa M. Valdizán, Zoltán Horváth, László Őrfi, Antonio Pineda‐Lucena, Emilie Bony, Gÿorgý Kéri, Germán Rivas, Ángel Pazos, Rafael Gozalbes, Héctor G. Pálmer, Adam Hurlstone, Piero Crespo

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Key concepts: MAPK/ERK pathway, Carcinogenesis, Cell biology, Chemistry, Anti-apoptotic Ras signalling cascade, Cancer research, Small molecule, Kinase