1991•Drug Development and Industrial PharmacyRequires access

Comparing the Compressibility of Ludipress with the Other Direct Tableting Agents by Using Acetaminophen as an Active Ingredient

Tamer Baykara, Gülengül Duman, K. Ş. Özşener, Şefıka ORDU, Betül ÖZATEŞ

Abstract

Ludipress is a direct tableting agent which acts as an unique component, is really a multi component. In this study Ludipress compressibility and powder technological properties are compared with the other kind of DC agents (Avicel PH 102, Elcema G 250 and Elcema P 050) which are structurally based on cellulose. Acetaminophen has been chosen as an active ingredient.The compression properties of powders and three direct tableting agent were investigated using the Heckel and Kawakita equations. Each formulations and compressed tablets which are compacted by hydraulic press with different pressure value were photographed by scanning electron microscope.As a result Ludipress shows stable flow properties and the dilution potential of Ludipress is lower than the other DC agents.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Tableting, Active ingredient, Compressibility, Flow properties, Ingredient, Scanning electron microscope, Compression (physics), Materials science