2010•Nature Structural & Molecular BiologyOpen access

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

Liwei Wang, Jin Kuk Yang, Venkataraman Kabaleeswaran, Amanda J. Rice, Anthony Cruz, Ah Young Park, Qian Yin, Ermelinda Damko, Se Bok Jang, Stefan Raunser, Carol V. Robinson, Richard M. Siegel, Thomas Walz, Hao Wu

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Key concepts: FADD, Death domain, Fas ligand, Fas receptor, Cell biology, Signal transducing adaptor protein, Caspase 8, Mutation

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The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations — Research Paper | ScholarLens