1998•Scandinavian Journal of Infectious DiseasesRequires access

A Trial Comparing Nucleoside Monotherapy with Sequential Therapy with 3 Drugs in HIV-infected Patients

Bernardino Roca

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Abstract

53 HIV-positive patients, 66% of them zidovudine-experienced, were randomized to receive monotherapy with zidovudine or sequential therapy with zidovudine, didanosine and zalcitabine. Clinical end points, CD4 cell count change, and analysis abnormalities showed better results with sequential therapy.

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What this paper is about

53 HIV-positive patients, 66% of them zidovudine-experienced, were randomized to receive monotherapy with zidovudine or sequential therapy with zidovudine, didanosine and zalcitabine. Clinical end points, CD4 cell count change, and analysis abnormalities showed better results with sequential therapy.

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Available abstract

53 HIV-positive patients, 66% of them zidovudine-experienced, were randomized to receive monotherapy with zidovudine or sequential therapy with zidovudine, didanosine and zalcitabine. Clinical end points, CD4 cell count change, and analysis abnormalities showed better results with sequential therapy.

Key concepts: Didanosine, Zalcitabine, Zidovudine, Medicine, Combination therapy, Internal medicine, Sida, Nucleoside analogue

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