A Trial Comparing Nucleoside Monotherapy with Sequential Therapy with 3 Drugs in HIV-infected Patients
Bernardino Roca
Abstract
Bernardino Roca
Abstract
53 HIV-positive patients, 66% of them zidovudine-experienced, were randomized to receive monotherapy with zidovudine or sequential therapy with zidovudine, didanosine and zalcitabine. Clinical end points, CD4 cell count change, and analysis abnormalities showed better results with sequential therapy.
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53 HIV-positive patients, 66% of them zidovudine-experienced, were randomized to receive monotherapy with zidovudine or sequential therapy with zidovudine, didanosine and zalcitabine. Clinical end points, CD4 cell count change, and analysis abnormalities showed better results with sequential therapy.
Key concepts: Didanosine, Zalcitabine, Zidovudine, Medicine, Combination therapy, Internal medicine, Sida, Nucleoside analogue