2009Chonnam Medical JournalRequires access

A Case of Henoch-Schönlein Purpura with Hemorrhagic Bullous Lesions

Kyung Yeon Lee, Jin Young Jeong, Jae Hee Suh, Joon Sung Kim

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Abstract

Henoch-Schonlein purpura (HSP) is the most common vasculitis in children and is characterized by cutaneous purpura, arthritis, abdominal pain, and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. We experienced a 9-year-old male patient who presented with colicky abdominal pain and arthralgia and severe hemorrhagic bullae in both lower legs. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis in small vessels of the dermis, and prominent IgA deposition was shown on capillary walls by direct immunofluorescence. His clinical symptoms were markedly improved with conservative management including corticosteroid therapy, which left no complications.

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What this paper is about

Henoch-Schonlein purpura (HSP) is the most common vasculitis in children and is characterized by cutaneous purpura, arthritis, abdominal pain, and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. We experienced a 9-year-old male patient who presented with colicky abdominal pain and arthralgia and severe hemorrhagic bullae in both lower legs. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis in small vessels of the dermis, and prominent IgA deposition was shown on capillary walls by direct immunofluorescence. His clinical symptoms were markedly improved with conservative management including corticosteroid therapy, which left no complications.

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Available abstract

Henoch-Schonlein purpura (HSP) is the most common vasculitis in children and is characterized by cutaneous purpura, arthritis, abdominal pain, and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. We experienced a 9-year-old male patient who presented with colicky abdominal pain and arthralgia and severe hemorrhagic bullae in both lower legs. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis in small vessels of the dermis, and prominent IgA deposition was shown on capillary walls by direct immunofluorescence. His clinical symptoms were markedly improved with conservative management including corticosteroid therapy, which left no complications.

Key concepts: Medicine, Palpable purpura, Purpura (gastropod), Buttocks, Henoch-Schonlein purpura, Rash, Skin biopsy, Dermatology

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