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2010•Hypertension in PregnancyRequires access

Comparison of Serum Levels and the Placental Expression of Resistin Between Patients with Preeclampsia and Normal Pregnant Women

Hyun‐Joo Seol, Min‐Jeong Oh, Min-Koo Yeo, Aeree Kim, Eung-Seok Lee, Hai‐Joong Kim

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Abstract

OBJECTIVE: The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression. METHODS: Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry. RESULTS: Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression. CONCLUSION: The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.

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What this paper is about

OBJECTIVE: The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression. METHODS: Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry. RESULTS: Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression. CONCLUSION: The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.

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Available abstract

OBJECTIVE: The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression. METHODS: Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry. RESULTS: Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression. CONCLUSION: The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.

Key concepts: Resistin, Medicine, Preeclampsia, Placenta, Internal medicine, Endocrinology, Immunohistochemistry, Pregnancy

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Comparison of Serum Levels and the Placental Expression of Resistin Between Patients with Preeclampsia and Normal Pregnant Women — Research Paper | ScholarLens