2011•Journal of BacteriologyOpen access

The Lipase LipA (PA2862) but Not LipC (PA4813) from Pseudomonas aeruginosa Influences Regulation of Pyoverdine Production and Expression of the Sigma Factor PvdS

Horst Funken, Andreas Knapp, Michael L. Vasil, Susanne Wilhelm, Karl‐Erich Jaeger, Frank Rosenau

Abstract

A key element in iron-dependent regulation of iron metabolism and virulence-related functions for Pseudomonas aeruginosa is the sigma factor PvdS. PvdS expression itself is also influenced by iron-independent stimuli. We show that pyoverdine production and pvdS expression depend on one of the two lipases of P. aeruginosa.

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Key concepts: Pyoverdine, Sigma factor, Pseudomonas aeruginosa, Biology, Microbiology, Siderophore, Virulence factor, Lipase