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1963•Journal of Bone and Joint SurgeryRequires access

Epiphyseal Avascular Necrosis and Its Relation to Longitudinal Bone Growth

H. Robert Brashear

Open publisher page 42 citations

Abstract

This is a study of the effect of epiphyseal avascular necrosis on longitudinal growth at the distal end of the femur of the rat. The findings demonstrate that proliferation of epiphyseal cartilage cells, and hence longitudinal growth, depends on an adequate epiphyseal circulation. Necrosis of the epiphysis causes marked change in the epiphyseal plate. These changes consist in walling off of the growth plate with bone and destruction of the epiphyseal cartilage. In the distal end of the femur of the rat this process appears to be irreversible.

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What this paper is about

This is a study of the effect of epiphyseal avascular necrosis on longitudinal growth at the distal end of the femur of the rat. The findings demonstrate that proliferation of epiphyseal cartilage cells, and hence longitudinal growth, depends on an adequate epiphyseal circulation. Necrosis of the epiphysis causes marked change in the epiphyseal plate. These changes consist in walling off of the growth plate with bone and destruction of the epiphyseal cartilage. In the distal end of the femur of the rat this process appears to be irreversible.

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Available abstract

This is a study of the effect of epiphyseal avascular necrosis on longitudinal growth at the distal end of the femur of the rat. The findings demonstrate that proliferation of epiphyseal cartilage cells, and hence longitudinal growth, depends on an adequate epiphyseal circulation. Necrosis of the epiphysis causes marked change in the epiphyseal plate. These changes consist in walling off of the growth plate with bone and destruction of the epiphyseal cartilage. In the distal end of the femur of the rat this process appears to be irreversible.

Key concepts: Epiphysis, Avascular necrosis, Epiphyseal plate, Cartilage, Femur, Necrosis, Medicine, Bone growth

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