2006•Infection and ImmunityOpen access
Role of the Porphyromonas gingivalis InlJ Protein in Homotypic and Heterotypic Biofilm Development
Cindy A. Capestany, Masae Kuboniwa, Il‐Young Jung, Yoonsuk Park, Gena D. Tribble, Richard J. Lamont
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Abstract
The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis.
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