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1971•Acta PaediatricaRequires access

COMPARISON OF GLOMERULAR FILTRATION RATE AND EFFECTIVE RENAL PLASMA FLOW DETERMINATIONS OBTAINED BY A SINGLE INJECTION TECHNIQUE AND BY MEANS OF A STANDARD CLEARANCE TECHNIQUE IN CHILDREN

B. VÖGELI, Hans Riedwyl, A Donath, O Oetliker

Open publisher page 34 citations

Abstract

Summary In children 28 values for glomerular filtration rate and 25 values for effective renal plasma flow were simultaneously obtained by means of the inulin‐ and PAH‐clearance and by means of a single injection method with 51Cr‐EDTA and 123I‐OIH. These were compared in an appropriate statistical model. The results show good agreement of the two methods. The single injection method can therefore be of value in childhood when only values for GFR and effective renal plasma flow are asked or especially if inappropriate urinary collection is expected or bladder catheterisation is contraindicated. It has no place in studies concerned with renal physiology or pathophysiology.

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Summary In children 28 values for glomerular filtration rate and 25 values for effective renal plasma flow were simultaneously obtained by means of the inulin‐ and PAH‐clearance and by means of a single injection method with 51Cr‐EDTA and 123I‐OIH. These were compared in an appropriate statistical model. The results show good agreement of the two methods. The single injection method can therefore be of value in childhood when only values for GFR and effective renal plasma flow are asked or especially if inappropriate urinary collection is expected or bladder catheterisation is contraindicated. It has no place in studies concerned with renal physiology or pathophysiology.

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Available abstract

Summary In children 28 values for glomerular filtration rate and 25 values for effective renal plasma flow were simultaneously obtained by means of the inulin‐ and PAH‐clearance and by means of a single injection method with 51Cr‐EDTA and 123I‐OIH. These were compared in an appropriate statistical model. The results show good agreement of the two methods. The single injection method can therefore be of value in childhood when only values for GFR and effective renal plasma flow are asked or especially if inappropriate urinary collection is expected or bladder catheterisation is contraindicated. It has no place in studies concerned with renal physiology or pathophysiology.

Key concepts: Medicine, Renal function, Urology, Effective renal plasma flow, Inulin, Renal blood flow, PAH clearance, Urinary system

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COMPARISON OF GLOMERULAR FILTRATION RATE AND EFFECTIVE RENAL PLASMA FLOW DETERMINATIONS OBTAINED BY A SINGLE INJECTION TECHNIQUE AND BY MEANS OF A STANDARD CLEARANCE TECHNIQUE IN CHILDREN — Research Paper | ScholarLens