1994Bioscience Biotechnology and BiochemistryRequires access

Biotransformation of Oleic Acid byMicrococcus luteusCells

Nobuyoshi Esaki, Shigeki Ito, Wolfgang A Blank, Kenji Soda

Open publisher page 16 citations

Abstract

We isolated bacterial strains tolerant to high concentrations of oleic acid from soil samples, and studied biotransformation of fatty acids with the bacteria. We found that a strain BL0–3 identified as Micrococcus luteus metabolized oleic acid to 10-hydroxystearic acid, 10-oxostearic acid, and 4-oxolauric acid. Palmitoleic acid and myristoleic acid also served as substrates in the biotransformation, and 10-oxopalmitic acid and 10-oxomyristic acid were produced, respectively. The formation of 4-oxolauric acid from oleic acid was inhibited by compounds which inhibit β-oxidation of fatty acids.

About this research paper

What this paper is about

We isolated bacterial strains tolerant to high concentrations of oleic acid from soil samples, and studied biotransformation of fatty acids with the bacteria. We found that a strain BL0–3 identified as Micrococcus luteus metabolized oleic acid to 10-hydroxystearic acid, 10-oxostearic acid, and 4-oxolauric acid. Palmitoleic acid and myristoleic acid also served as substrates in the biotransformation, and 10-oxopalmitic acid and 10-oxomyristic acid were produced, respectively. The formation of 4-oxolauric acid from oleic acid was inhibited by compounds which inhibit β-oxidation of fatty acids.

Why it matters

OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

We isolated bacterial strains tolerant to high concentrations of oleic acid from soil samples, and studied biotransformation of fatty acids with the bacteria. We found that a strain BL0–3 identified as Micrococcus luteus metabolized oleic acid to 10-hydroxystearic acid, 10-oxostearic acid, and 4-oxolauric acid. Palmitoleic acid and myristoleic acid also served as substrates in the biotransformation, and 10-oxopalmitic acid and 10-oxomyristic acid were produced, respectively. The formation of 4-oxolauric acid from oleic acid was inhibited by compounds which inhibit β-oxidation of fatty acids.

Key concepts: Biotransformation, Oleic acid, Palmitoleic acid, Micrococcus luteus, Chemistry, Fatty acid, Bacteria, Biochemistry

Related papers

Back to paper searchBrowse research topicsOriginal source
Biotransformation of Oleic Acid byMicrococcus luteusCells — Research Paper | ScholarLens