2000•Journal of Clinical MicrobiologyOpen access

Heterogeneous Vancomycin Resistance in Methicillin-Resistant Staphylococcus aureus Strains Isolated in a Large Italian Hospital

Anna Marchese, G. Balistreri, E. Tonoli, Eugenio A. Debbia, Gian Carlo Schito

Abstract

Of 179 methicillin-resistant Staphylococcus aureus strains isolated from 1997 to 1998, two strains (1.1%) gave subclones for which the vancomycin MICs were 8 mg/liter. Pulsed-field gel electrophoresis showed identical restriction patterns for both isolates, suggesting transfer of a single clone between two different patients.

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Key concepts: Microbiology, Staphylococcus aureus, Micrococcaceae, Vancomycin, clone (Java method), Biology, Staphylococcal infections, Pulsed-field gel electrophoresis